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課程名稱 |
核醣核酸生物學
Rna Biology |
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開課學期 |
107-2 |
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授課對象 |
生命科學院 生命科學所 |
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授課教師 |
朱家瑩 |
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課號 |
LS5049 |
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課程識別碼 |
B21 U1700 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期四3,4(10:20~12:10) |
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上課地點 |
生科4C |
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備註 |
與朱雪萍合授
總人數上限：20人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1072LS5049_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
The role of RNA in regulating gene expression has become a topic of intense interest. This course will focus on RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in various model systems, including yeast, Drosophila, mammals, and viral infection. The course will also highlight the application of this knowledge in therapeutics and research at the final section. |
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課程目標 |
This course will provide a comprehensive interpretation that is intended for students who are interest in RNA, the regulation of gene expression, genetics, genomics or molecular biology. |
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課程要求 |
Students are asked to develop a consolidated version of research proposal during the class, with a stepwise writing of abstract, research rationales, specific aims and the final proposal in different weeks. A final oral presentation is also required for each student. Grading standard is based on a mid-term quiz, the achievement of each assignment, and the oral presentation of research proposal. |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
待補 |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
2/21 |
Organization/ Writing the Research Proposal |
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第2週 |
2/28 |
Holiday |
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第3週 |
3/07 |
Introduction/ RNA synthesis |
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第4週 |
3/14 |
RNA splicing and processing (* 曾惠群, 朱怡寧, 陳若文) |
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第5週 |
3/21 |
RNA editing and modification |
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第6週 |
3/28 |
RNA degradation (*江盈盈, 韓天恒) |
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第7週 |
4/04 |
Holiday |
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第8週 |
4/11 |
RNAi (I): eukaryotic RNAi (*邱培真, 范嘉恆) |
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第9週 |
4/18 |
Organizing your proposal (turn in topics, hypothesis, abstract w/ specific aims) |
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第10週 |
4/25 |
RNAi (II): prokaryotic RNAi (*陳理為, 張凌誌) |
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第11週 |
5/02 |
Small non-coding RNA (I): miRNAs and translational control in animals (*陳雲飛, 沈宏智) |
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第12週 |
5/09 |
Small non-coding RNA (II): piRNAs and RNA-directed DNA methylation (turn in Background and Significance) |
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第13週 |
5/16 |
Long non-coding RNAs (*包鈺玄, 鄭妙怡, 張耘誌) |
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第14週 |
5/23 |
Natural antisense and circular RNAs (*陳昱甄, 洪鎰保) |
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第15週 |
5/30 |
Student Proposal Presentation (1) (Written proposal due)洪鎰保, 江盈盈, 張凌誌, 陳雲飛 |
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第16週 |
6/06 |
Student Proposal Presentation (2) 沈宏智, 陳昱甄, 鄭妙怡, 張耘誌 |
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第17週 |
6/13 |
Student Proposal Presentation (3) 范嘉恆, 包鈺玄, 邱培真, 朱怡寧 |
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第18週 |
6/20 |
Student Proposal Presentation (4) 陳若文, 曾惠群, 陳理為, 韓天恒 |
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